Leukemia FISH probes


             Fluorescence in situ hybridization(FISH) is widely applicable in leukemia detection, integrating easy operation with visually clear results. Chromosome t (22 : 9)(q11.23 : q34.12) translocations can be detected in 95% of chronic myelogenous leukemia(CML); this fusion gene is also an important evaluating indicator for CML diagnosis. The translocation t(15 : 17)(q24.1 : q21.2) , which results in the PML/RARα fusion gene, is the most specific genetic marker in acute promyelocytic leukemia (APL); it is also an important evaluating indicator for medication monitoring in this disease.

     GenomePrecision introduced Cytotest’s FISH probes, which are high-quality probes for clinical use.


Product list

  Please contact us for more probes

Chronic myelogenous leukemia(CML)

Code

Product

Locus

Pack size

CT-PAC302-10-GO

BCR-ABL1 Fusion/Translocation FISH   Probe Kit

22q11.23

9q34.12

10 Assay/Kit

CT-PAC110-10-GOA

BCR-ABL1/ASS1 Tri-color Fusion/Translocation FISH Probe Kit

22q11.23

9q34.12

9q34.11

10 Assay/Kit


Chronic lymphocytic leukemia(CLL)

Code

Product

Locus

Pack size

CT-PAC352-10-OG

ATM/CCP11 FISH Probe Kit

11q22.3

11p11-q11

10 Assay/Kit

CT-CCP012-10-G

CT-CCP012-10-A

CCP12 FISH Probe

12p11-q11

10 Assay/Kit

CT-PAC360-10-OG

D13S319/LAMP1 FISH Probe Kit

13q14.2

13q34

10 Assay/Kit

CT-PAC201-10-OG

IGH Break Apart FISH Probe Kit

14q32.33

10 Assay/Kit

CT-PAC018-10-OG

MYB/CCP6 FISH Probe Kit

6q23.3

6p11-q11

10 Assay/Kit

CT-PAC351-10-OG

TP53/CCP17 FISH Probe Kit

17p13.1

17p11-q11

10 Assay/Kit

CT-PAC222-10-GO

IGH-CCND1 Fusion/Translocation FISH Probe Kit

14q32.33

11q13.3

10 Assay/Kit

CT-PAC221-10-GO

IGH-BCL2 Fusion/Translocation FISH

Probe Kit

14q32.33,

18q21.33

10 Assay/Kit


 

            Acute myeloblastic leukemia(AML)

Code

Product

Locus

Pack size

CT-PAC303-10-GO

RUNX1-RUNX1T1 Fusion/Translocation FISH Probe Kit (Previously known as   AML1-ETO)

21q22.12

8q21.3

10 Assay/Kit

CT-PAC304-10-OG

PML-RARA Fusion/Translocation FISH Probe Kit

15q24.1

17q21.2

10 Assay/Kit

CT-PAC328-10-OG

CBFB Break Apart FISH Probe Kit

16q22.1

10 Assay/Kit

CT-PAC326-10-OG

KMT2A Break Apart FISH Probe Kit

11q23.3

10 Assay/Kit

CT-PAC071-10-GO

MECOM Break Apart FISH Probe Kit

3q26.2

10 Assay/Kit

CT-PAC109-10-GO

DEK-NUP214 Fusion/Translocation FISH Probe Kit

6p22.3

9q34.13

10 Assay/Kit

CT-PAC094-10-GO

RPN1-MECOM Fusion/Translocation

FISH Probe Kit

3q21.3

3q26.2

10 Assay/Kit

CT-PAC351-10-OG

TP53/CCP17 FISH Probe Kit

17p13.1

17p11-q11

10 Assay/Kit


            Chronic myeloproliferative neoplasm(CMPN)

Code

Product

Locus

Pack size

CT-PAC302-10-GO

BCR-ABL1Fusion/Transloca tion FISH    Probe Kit

22q11.23

9q34.12

10 Assay/Kit

CT-PAC091-10-GO

PDGFRA Break Apart FISH Probe Kit

4q12

10 Assay/Kit

CT-PAC210-10-OG

PDGFRB Break Apart FISH Probe Kit

5q32

10 Assay/Kit

CT-PAC056-10-GO

FGFR1 Break Apart FISH Probe Kit

8p11.23

10 Assay/Kit


            Acute lymphoblastic leukemia(ALL)

Code

Product

Locus

Pack size

CT-PAC302-10-GO

BCR-ABL1 Fusion/Translocation FISH    Probe Kit

22q11.23

9q34.12

10 Assay/Kit

CT-LSP263-10-O

LSP MPO FISH Probe

17q22

10 Assay/Kit

CT-PAC305-10-OG

ETV6-RUNX1 Fusion/Translocation FISH Probe Kit

12p13.2

21q22.12

10 Assay/Kit

CT-PAC201-10-OG

IGH Break Apart FISH Probe Kit

14q32.33

10 Assay/Kit

CT-PAC114-10-OG

CRLF2 Break Apart FISH Probe Kit

Xp22.33

(Yp11.32)

10 Assay/Kit

CT-PAC210-10-OG

PDGFRB Break Apart FISH Probe Kit

5q32

10 Assay/Kit

CT-PAC351-10-OG

TP53/CCP17 FISH Probe Kit

17p13.1

17p11-q11

10 Assay/Kit

CT-PAC208-10-OG

MYC  Break Apart FISH Probe

Kit

8q24.21

10 Assay/Kit

CT-PAC172-10-GO

FIP1L1/CHIC2 FISH Probe Kit

4q12

4q12

10 Assay/Kit

CT-PAC308-10-GO

TCF3-PBX1 Fusion/Translocation FISH

Probe Kit

19p13.3

1q23.3

10 Assay/Kit

CT-PAC307-10-GO

KMT2A-AFF1 Fusion/Translocation FISH Probe Kit

11q23.3

4q21.3

10 Assay/Kit


             Multiple myeloma

Code

Product

Locus

Pack size

CT-PAC222-10-GO

IGH-CCND1 Fusion/Translocation FISH　Probe   Kit

14q32.33

11q13.3

10 Assay/Kit

CT-PAC309-10-GO

IGH-FGFR3 Fusion/Translocation FISH　Probe   Kit

14q32.33

4p16.3

10 Assay/Kit

CT-PAC310-10-GO

IGH-MAF Fusion/Translocation FISH

Probe Kit

14q32.33

16q23.2

10 Assay/Kit

CT-PAC045-10-OG

FOXO1 Break Apart FISH Probe Kit

13q14.11

10 Assay/Kit

CT-PAC351-10-OG

TP53/CCP17 FISH Probe Kit

17p13.1

17p11-q11

10 Assay/Kit

CT-PAC126-10-GO

CDKN2C/CKS1B FISH Probe Kit

1p32.3, 1q21.3

10 Assay/Kit

CT-PAC201-10-OG

IGH Break Apart FISH Probe Kit

14q32.33

10 Assay/Kit

CT-PAC311-10-GO

IGH-MAFB Fusion/Translocation FISH

Probe Kit

14q32.33

20q12

10 Assay/Kit


            Myelodysplstic syndrome(MDS)

Code

Product

Locus

Pack size

CT-PAC353-10-OG

EGR1/D5S23, D5S721 FISH Probe Kit

5q31.2

5p15.2

10 Assay/Kit

CT-PAC357-10-OG

D7S486/CCP7 FISH Probe Kit

7q31.2

7p11-q11

10 Assay/Kit

CT-PAC130-10-OG

FGFR1/CCP8 FISH Probe Kit

8p11.23

8p11-q11

10 Assay/Kit

CT-LSP056-10-O

LSP D20S108 FISH Probe

20q12

10 Assay/Kit

CT-PAC326-10-OG

KMT2A Break Apart FISH Probe Kit

11q23.3

10 Assay/Kit

CT-CCP124-10-O

CT-CCP124-10-G

CEPYCCPY (DYZ1) FISH Probe

Yp11-q11

10 Assay/Kit

CT-PAC351-10-OG

TP53/CCP17 FISH Probe Kit

17p13.1

17p11-q11

10 Assay/Kit