PNA telomere FISH probes

    Peptide nucleic acids(PNA) are the new DNA mimics that are capable of recognizing and binding to DNA or RNA sequences to form stable double helix structure. Since PNA carries no negative charge and there is no electrostatic repulsion between DNA and RNA strands, PNA shows greater stability and specificity in binding. PNA can be widely used in the following fields:

1) miRNA inhibitors

2) Antisense drug research and treatment

3) Molecular biology and functional genomics

4) Diagnostic molecular probes: telomere FISH probes; Lightup probes; SNP probes; Microarray probes; Nucleic acid biosensor probes; telomere probes.

PNA probes have a special chemical constitution of electric neutrality and have high specificity and sensitivity, allowing it to be used efficiently in fluorescent in situ hybridization(FISH) technologies. PNA-DNA hybridization can be completed rapidly within two hours, and background hybridization signals can be significantly reduced.

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